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Submit ReviewTUG 424
说明： FFA1 (GPR40) agonist
化学名： 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoic acid
纯度： ≥99% (HPLC)
生物活性 for TUG 424
Agonist of the free fatty acid receptor FFA1 (GPR40) (EC50 = 32 nM). Enhances glucose-stimulated insulin secretion in INS-1E cells at 100 nM.
许可信息
Sold under license from the University of Southern Denmark.
技术数据 for TUG 424
| 分子量 | 264.32 |
| 公式 | C18H16O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 1082058-99-8 |
| Smiles | CC1=CC=CC=C1C#CC2=CC=C(CCC(O)=O)C=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for TUG 424
参考文献 for TUG 424
参考文献是支持产品生物活性的出版物。
Christiansen et al (2008) Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA1/GPR40), a potential target for the treatment of type II diabetes. J.Med.Chem. 51 7061 PMID: 18947221
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关键词: TUG 424, TUG 424 supplier, TUG424, free, fatty, acid, receptors, ffa1, GPR40, agonists, Free, Fatty, Acid, Receptors, 3795, Tocris Bioscience
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