U 99194 maleate

Name: U 99194 maleate
Brand: Tocris Bioscience
SKU: 1357

Cat. No. 1357 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1357 has been discontinued.

View all D<sub>3</sub> Receptors products.

说明： Potent and selective D₃ antagonist

别名： PNU 99194

化学名： 2,3-Dihydro-5,6-dimethoxy-N, N-dipropyl-1H-inden-2-amine maleate

纯度： ≥98% (HPLC)

说明书

引用文献 (2)

文献 (3)

生物活性技术数据说明书参考文献

生物活性 for U 99194 maleate

U 99194 maleate is a potent, selective D₃ antagonist. K_i values are 160, 2281 and > 10000 nM for human cloned D₃, D₂ and D₄ receptors respectively.

技术数据 for U 99194 maleate

分子量	393.48
公式	C₁₇H₂₇NO₂.C₄H₄O₄
储存	Store at RT
纯度	≥98% (HPLC)
CAS Number	234757-41-6
PubChem ID	11957713
InChI Key	FSIQDESGRQTFNN-BTJKTKAUSA-N
Smiles	OC(=O)\C=C/C(O)=O.CCCN(CCC)C1CC2=C(C1)C=C(OC)C(OC)=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for U 99194 maleate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for U 99194 maleate

参考文献是支持产品生物活性的出版物。

Audinot et al (1998) A comparative in vitro and in vivo pharmacological characterization of the novel DA D₃ receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. J.Pharmacol.Exp.Ther. 287 187 PMID: 9765337

Clifford and Waddington (1998) Heterogeneity of behavioural profile between three putative selective D₃ DA receptor antagonists using an ethologically based approach. Psychopharmacology 136 284 PMID: 9566814

LaHoste et al (2000) DA D₁ receptors synergize with D₂, but not D₃ or D₄, receptors in the striatum without the involvement of action potentials. J.Neurosci. 20 6666 PMID: 10964971

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关键词: U 99194 maleate, U 99194 maleate supplier, Potent, selective, D3, antagonists, Dopamine, Receptors, dopaminergic, U99194, maleate, PNU99194, PNU, 99194, 1357, Tocris Bioscience

2 篇 U 99194 maleate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 U 99194 maleate 的部分引用包括：

Newton et al (2016) Examining the Effects of Sodium Ions on the Binding of Antagonists to DA D 2 and D 3 Receptors PLoS One 11 e0158808 PMID: 27379794

Bastianetto et al (2006) Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation. BMC Neurosci 7 28 PMID: 16573831

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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

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