UDP disodium salt

Name: UDP disodium salt
Brand: Tocris Bioscience
SKU: 3111
Rating: 5 (1 reviews)

Cat. No. 3111 2 篇引用文献 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Endogenous ligand; competitive antagonist at P2Y₁₄ receptors

化学名： Uridine-5'-diphosphate disodium salt

纯度： ≥97% (HPLC)

说明书

引用文献 (2)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for UDP disodium salt

UDP disodium salt is an endogenous P2Y receptor agonist which preferentially activates P2Y₆. Shown to be a competitive antagonist at P2Y₁₄ receptors.

技术数据 for UDP disodium salt

分子量	448.12
公式	C₉H₁₂N₂Na₂O₁₂P₂
储存	Store at -20°C
纯度	≥97% (HPLC)
CAS Number	27821-45-0
PubChem ID	11957711
InChI Key	ZQKVPFKBNNAXCE-WFIJOQBCSA-L
Smiles	[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N1C=CC(=O)NC1=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for UDP disodium salt

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	44.81	100

制备储备液 for UDP disodium salt

以下数据基于产品分子量 448.12。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.23 mL	11.16 mL	22.32 mL
5 mM	0.45 mL	2.23 mL	4.46 mL
10 mM	0.22 mL	1.12 mL	2.23 mL
50 mM	0.04 mL	0.22 mL	0.45 mL

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产品说明书 for UDP disodium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for UDP disodium salt

参考文献是支持产品生物活性的出版物。

Ralevic and Burnstock (1998) Receptors for purines and pyrimidines. Pharmacol.Rev. 50 413 PMID: 9755289

Fricks et al (2008) UDP is a competitive antagonist at the human P2Y₁₄ receptor. J.Pharmacol.Exp.Ther. 325 588 PMID: 18252808

If you know of a relevant reference for UDP disodium salt, please let us know.

按标靶查看相关产品

Purinergic (P2Y) Receptors

关键词: UDP disodium salt, UDP disodium salt supplier, Endogenous, ligands, competitive, antagonists, P2Y14, receptors, Purinergic, purinoceptors, P2Y, Receptors, 3111, Tocris Bioscience

2 篇 UDP disodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 UDP disodium salt 的部分引用包括：

Obba et al (2015) The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML. Alcohol Clin Exp Res 11 1114 PMID: 26029847

Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050 PMID: 24048730

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P2Y6 activation (P2Y6).

By Anonymous on 10/22/2018

分析类型： Ex Vivo

种属： Mouse

Applied directly on a tissue slice to activate P2Y receptors (P2Y6 mostly). Elicited expected cellular response.

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

P2X and P2Y Receptors Scientific Review

Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.