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Submit ReviewUNC 926 hydrochloride
说明： L3MBTL1 domain inhibitor
化学名： (3-Bromophenyl)[4-(1-prrolidinyl)-1-piperidinyl]methanone hydrochloride
纯度： ≥99% (HPLC)
生物活性 for UNC 926 hydrochloride
UNC 926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.
技术数据 for UNC 926 hydrochloride
| 分子量 | 373.72 |
| 公式 | C16H21BrN2O.HCl |
| 储存 | Desiccate at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 1782573-49-2 |
| PubChem ID | 90488947 |
| InChI Key | DPPMBBHOXQOMJI-UHFFFAOYSA-N |
| Smiles | BrC1=CC=CC(C(N2CCC(N3CCCC3)CC2)=O)=C1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for UNC 926 hydrochloride
参考文献 for UNC 926 hydrochloride
参考文献是支持产品生物活性的出版物。
Herold et al (2012) Structure-activity relationships of methyl-lysine reader antagonists. Med.Chem.Comm 3 45
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关键词: UNC 926 hydrochloride, UNC 926 hydrochloride supplier, UNC926, Methyl-lysine, Kme, readers, antagonists, MBT, domains, L3MBTL1, histones, epigenetics, Other, Transcription, Factors, Domains, 4516, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.