Urotensin II (human)

Discontinued Product

1642 has been discontinued.

View all Urotensin-II Receptors products.
说明: Endogenous vasoactive agonist for the UT receptor
说明书
引用文献
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生物活性 for Urotensin II (human)

Urotensin II (human) is a potent endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo, effects which vary between species. Also has been shown to mediate bronchoconstriction.

技术数据 for Urotensin II (human)

分子量 1388.57
公式 C64H85N13O18S2
序列 ETPDCFWKYCV

(Modifications: Disulfide bridge between 5 - 10)

储存 Desiccate at -20°C
CAS Number 251293-28-4
PubChem ID 46225600
InChI Key HFNHAPQMXICKCF-USJMABIRSA-N
Smiles [H]N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Urotensin II (human)

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参考文献 for Urotensin II (human)

参考文献是支持产品生物活性的出版物。

Coulouarn et al (1998) Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurones of the spinal cord. Proc.Natl.Acad.Sci.U.S.A. 95 15803 PMID: 9861051

Maguire and Davenport (2002) Is urotensin-II the new endothelin? Br.J.Pharmacol 137 579 PMID: 12381671

Nothacker et al (1999) Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nat.Cell.Biol. 1 383 PMID: 10559967

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关键词: Urotensin II (human), Urotensin II (human) supplier, Endogenous, vasoactive, agonists, UT, receptor, Receptors, Urotensin-II, UrotensinII, (human), 1642, Tocris Bioscience

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