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Vinpocetine

Cat. No. 0757 2 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0757 has been discontinued.

View all Voltage-gated Sodium (Na<sub>V</sub>) Channels products.
说明： Na+ channel blocker
化学名： (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
纯度： ≥99% (HPLC)
说明书
引用文献 (2)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Vinpocetine

Vinpocetine is a phosphodiesterase inhibitor, selective for PDE1 (IC50 = 21 μM). Also blocks voltage-gated Na+ channels.

技术数据 for Vinpocetine

分子量 350.46
公式 C22H26N2O2
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 42971-09-5
PubChem ID 443955
InChI Key DDNCQMVWWZOMLN-IRLDBZIGSA-N
Smiles O=C(OCC)C5=C[C@@]2(CC)[C@@]1([H])C4=C(C3=CC=CC=C3N45)CCN1CCC2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Vinpocetine

参考文献是支持产品生物活性的出版物。

Hagiwara et al (1984) Effect of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem.Pharmacol. 33 453 PMID: 6322804

Molnar and Erdo (1995) Vinpocetine is as potent as phen. to block voltage-gated Na+ channels in rat cortical neurons. Eur.J.Pharmacol. 273 303 PMID: 7737339

Merck Index 12 10128

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关键词: Vinpocetine, Vinpocetine supplier, PDE1, inhibitors, inhibits, Na+, channel, blockers, Phosphodiesterases, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Voltage-gated, 0757, Tocris Bioscience

2 篇 Vinpocetine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Vinpocetine 的部分引用包括：

Lee et al (2015) Vinpocetine inhibits Streptococcus pneumoniae-induced upregulation of mucin MUC5AC expression via induction of MKP-1 phosphatase in the pathogenesis of otitis media. EMBO Mol Med 194 5990 PMID: 25972475

Robichaud et al (2002) Assessing the emetic potential of PDE4 inhibitors in rats. Br J Pharmacol 135 113 PMID: 11786486

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