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Submit ReviewVULM 1457
Discontinued Product
2988 has been discontinued.
说明： ACAT inhibitor
化学名： N-[2,6-bis(1-Methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea
纯度： ≥99% (HPLC)
生物活性 for VULM 1457
VULM 1457 is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. Decreases cholesterol levels in the plasma and liver of diabetic-hypercholesterolemic rats.
技术数据 for VULM 1457
| 分子量 | 449.57 |
| 公式 | C25H27N3O3S |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 228544-65-8 |
| PubChem ID | 9933427 |
| InChI Key | XFFITGBWVLQNCD-UHFFFAOYSA-N |
| Smiles | O=C(NC3=C(C(C)C)C=CC=C3C(C)C)NC(C=C2)=CC=C2SC1=CC=C([N+]([O-])=O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for VULM 1457
参考文献 for VULM 1457
参考文献是支持产品生物活性的出版物。
Adameova et al (2006) Protective effect of SimV. and VULM 1457 in ischaemic-reperfused myocardium of the diabetic-hypercholesterolemic rats. Pharmazie 61 807 PMID: 17020164
Adameova et al (2007) The myocardial infarct size-limiting and antiarrhythmic effects of acyl-CoA: cholesterol acyltransferase inhibitor VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against ischaemia/reperfusion injury both in vitro and in v Eur.J.Pharmacol. 576 114 PMID: 17764671
Vojtassakova et al (2007) Effect of VULM 1457, an ACAT inhibitor, on serum lipid levels and on real time red blood cell flow in diabetic and non-diabetic hamsters fed high cholesterol-lipid diet. Gen.Physiol.Biophys. 26 254 PMID: 18281742
关键词: VULM 1457, VULM 1457 supplier, Acyl-CoA, cholesterol, acyltransferase, ACAT, inhibitors, inhibits, Transferases, VULM1457, Acyl-CoA:Cholesterol, Acyltransferase, 2988, Tocris Bioscience
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