WAY 267464 dihydrochloride

Cat. No. 3933 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Potent non-peptide oxytocin receptor agonist

化学名： N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamide dihydrochloride

纯度： ≥97% (HPLC)

引用文献 (5)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for WAY 267464 dihydrochloride

WAY 267464 dihydrochloride is a potent, selective non-peptide oxytocin receptor (OTR) agonist (K_i = 58.4 nM at human OTR). Exhibits anxiolytic-like effects. May have therapeutic potential for the treatment of psychosis and schizophrenia.

许可信息

Sold for research purposes under agreement from Pfizer Inc.

技术数据 for WAY 267464 dihydrochloride

分子量	654.59
公式	C₃₂H₃₅N₇O₄.2HCl
储存	Store at -20°C
纯度	≥97% (HPLC)
CAS Number	1432043-31-6
PubChem ID	71555165
InChI Key	OTFWXMFLPMUDFP-UHFFFAOYSA-N
Smiles	CN(N=C3)C1=C3CN(C(C4=CC=C(CNC(N5CCN(CC6=CC(O)=CC(O)=C6)CC5)=O)C(C)=C4)=O)C(C=CC=C2)=C2N1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for WAY 267464 dihydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	52.37	80
	water	3.27	5

制备储备液 for WAY 267464 dihydrochloride

以下数据基于产品分子量 654.59。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.8 mM	1.91 mL	9.55 mL	19.1 mL
4 mM	0.38 mL	1.91 mL	3.82 mL
8 mM	0.19 mL	0.95 mL	1.91 mL
40 mM	0.04 mL	0.19 mL	0.38 mL

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产品说明书 for WAY 267464 dihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for WAY 267464 dihydrochloride

参考文献是支持产品生物活性的出版物。

Ring et al (2010) Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxyt. receptor agonist. Neuropharmacology 58 6 PMID: 19615387

If you know of a relevant reference for WAY 267464 dihydrochloride, please let us know.

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关键词: WAY 267464 dihydrochloride, WAY 267464 dihydrochloride supplier, WAY267464, dihydrochloride, oxytocin, agonists, OT, receptors, non-peptide, pfizer, Oxytocin, Receptors, 3933, Tocris Bioscience