主页 / 药理学 / Enzymes / Phosphodiesterases / Phosphodiesterase Inhibitors / Zardaverine

Zardaverine

Cat. No. 1046 4 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1046 has been discontinued.

View all Phosphodiesterases products.
说明： PDE3/4 inhibitor
化学名： 6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone
纯度： ≥98% (HPLC)
说明书
引用文献 (4)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Zardaverine

Zardaverine is a phosphodiesterase inhibitor, selective for PDE3 and 4 (IC50 values are 0.5 and 0.8 μM respectively).

技术数据 for Zardaverine

分子量 268.22
公式 C12H10F2N2O3
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 101975-10-4
PubChem ID 5723
InChI Key HJMQDJPMQIHLPB-UHFFFAOYSA-N
Smiles COC1=C(OC(F)F)C=CC(=C1)C1=NNC(=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Zardaverine

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Zardaverine

参考文献是支持产品生物活性的出版物。

Galvan and Schudt (1990) Actions of the phosphodiesterase inhibitor zardaverine on guinea pig ventricular muscle. Naunyn Schmiedebergs Arch.Pharmacol. 342 221 PMID: 1700309

Kilian et al (1989) Is phosphodiesterase inhibition a relevant bronchospasmolytic principle? Agents Actions Suppl. 28 331 PMID: 2683636

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Phosphodiesterase Inhibitors

关键词: Zardaverine, Zardaverine supplier, PDE3/4, inhibitors, inhibits, Phosphodiesterases, 1046, Tocris Bioscience

4 篇 Zardaverine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Zardaverine 的部分引用包括：

Lee et al (2012) The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature 492 123 PMID: 23143333

Navarro et al (2015) Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. J Neurosci 35 6639 PMID: 25926444

Gulyani et al (2009) Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells. Exp Neurol 215 236 PMID: 19013457

Zerani et al (2004) Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea. Pain 183 279 PMID: 15531716

Zardaverine 的评论

目前没有该产品的评论。 Be the first to review Zardaverine and earn rewards!

Have you used Zardaverine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review