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Submit ReviewZD 7114 hydrochloride
Discontinued Product
0930 has been discontinued.
View all Adrenergic β<sub>3</sub> Receptors products.
说明： β3 agonist
别名： ICI D7114
化学名： (S)-4-[2-Hydroxy-3-phenoxypropylaminoethoxy]-N-(2-methoxyethyl)phenoxyacetamide hydrochloride
生物活性 for ZD 7114 hydrochloride
ZD 7114 hydrochloride is a β3-adrenoceptor agonist.
Active Metabolite also available.
许可信息
Sold with the permission of AstraZeneca UK Ltd.
技术数据 for ZD 7114 hydrochloride
| 分子量 | 454.95 |
| 公式 | C22H30N2O6.HCl |
| 储存 | Store at RT |
| CAS Number | 129689-28-7 |
| PubChem ID | 9890216 |
| InChI Key | KCAMZVQSGDBGGF-FERBBOLQSA-N |
| Smiles | O[C@H](COC2=CC=CC=C2)CNCCOC1=CC=C(OCC(NCCOC)=O)C=C1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for ZD 7114 hydrochloride
分析证书目前不在网上提供。
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参考文献 for ZD 7114 hydrochloride
参考文献是支持产品生物活性的出版物。
Growcott et al (1993) Evaluation of ICI D7114, a putative stimulant of brown adipocytes, on histamine-contracted guinea-pig ileum. Br.J.Pharmacol. 109 1212 PMID: 8104647
Savontaus et al (1998) Effects of ZD7114, a selective β3-adrenoceptor agonist, on neuroendocrine mechanisms controlling energy balance. Eur.J.Pharmacol. 347 265 PMID: 9653893
How (1993) β3-Adrenergic agonists. Drugs Future 18 529
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关键词: ZD 7114 hydrochloride, ZD 7114 hydrochloride supplier, β3-adrenoceptor, b3-adrenoceptor, β3-adrenergic, b3-adrenergic, agonists, Receptors, ZD7114, hydrochloride, ICID7114, AstraZeneca, ICI, D7114, Adrenergic, Beta-3, 0930, Tocris Bioscience
2 篇 ZD 7114 hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 ZD 7114 hydrochloride 的部分引用包括：
Suárez et al (2014) Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. Dis Model Mech 7 129 PMID: 24159189
Baker et al (2011) Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses. FASEB J 25 4486 PMID: 21865315
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Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.