ICI 215,001 hydrochloride

Discontinued Product

0929 has been discontinued.

View all Adrenergic &beta;<sub>3</sub> Receptors products.
Description: β3 agonist
Chemical Name: (S)-4-[2-Hydroxy-3-phenoxypropylaminoethoxy]phenoxyacetic acid hydrochloride
Datasheet
Citations (2)
Reviews
Literature (1)

Biological Activity for ICI 215,001 hydrochloride

The active metabolite of ZD 7114 (Cat. No. 0930).

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data for ICI 215,001 hydrochloride

M. Wt 397.86
Formula C19H23NO6.HCl
Storage Store at RT
CAS Number 140850-02-8
PubChem ID 56972157
InChI Key ISFZQNYGEYAUCR-RSAXXLAASA-N
Smiles O[C@H](COC2=CC=CC=C2)CNCCOC1=CC=C(OCC(O)=O)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for ICI 215,001 hydrochloride

Certificate of Analysis is currently unavailable on-line.
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References for ICI 215,001 hydrochloride

References are publications that support the biological activity of the product.

How (1993) β3Adrenergic agonists. Drugs Future 18 529

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2 Citations for ICI 215,001 hydrochloride

Citations are publications that use Tocris products. Selected citations for ICI 215,001 hydrochloride include:

Suárez et al (2014) Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. Dis Model Mech 7 129 PMID: 24159189

Littmann et al (2015) Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands. PLoS One 355 183 PMID: 26306764


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.