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Submit Review0929 has been discontinued.
View all Adrenergic β<sub>3</sub> Receptors products.The active metabolite of ZD 7114 (Cat. No. 0930).
Sold with the permission of AstraZeneca UK Ltd.
M. Wt | 397.86 |
Formula | C19H23NO6.HCl |
Storage | Store at RT |
CAS Number | 140850-02-8 |
PubChem ID | 56972157 |
InChI Key | ISFZQNYGEYAUCR-RSAXXLAASA-N |
Smiles | O[C@H](COC2=CC=CC=C2)CNCCOC1=CC=C(OCC(O)=O)C=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
How (1993) β3Adrenergic agonists. Drugs Future 18 529
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Citations are publications that use Tocris products. Selected citations for ICI 215,001 hydrochloride include:
Suárez et al (2014) Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. Dis Model Mech 7 129 PMID: 24159189
Littmann et al (2015) Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands. PLoS One 355 183 PMID: 26306764
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.