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View all Non-selective Adrenergic α Receptors products.Dihydroergocristine mesylate is a 5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.
M. Wt | 707.84 |
Formula | C35H41N5O5.CH3SO3H |
Storage | Store at RT |
Purity | ≥98% (HPLC) |
CAS Number | 24730-10-7 |
PubChem ID | 444034 |
InChI Key | SPXACGZWWVIDGR-SPZWACKZSA-N |
Smiles | CS(=O)(O)=O.[H][C@]4([C@@]([H])3C[C@@H]([C@@](N[C@@]5([C@H](C)C)C(N([C@@]([H])(CC8=CC=CC=C8)C(N7[C@]([H])6CCC7)=O)[C@@]6(O)O5)=O)=O)CN4C)CC1=CNC2=C1C3=CC=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Drago (1988) Dihydroergocristine and memory alterations of aged male rats. Pharmacol.Biochem.Behav. 30 961 PMID: 3147464
Keywords: Dihydroergocristine mesylate, Dihydroergocristine mesylate supplier, Partial, α-adrenoceptors, α-adrenoceptor, alpha-adrenoceptors, agonists, Non-Selective, dopamine, receptors, partial, α-adrenergic, alpha-adrenergic, a-adrenergic, 5-HT, antagonists, dopaminergic, D2-like, 5-Hydroxytryptamine, Serotonin, 5-HT3, Non-selective, Adrenergic, Alpha, Receptors, Dopamine, 0474, Tocris Bioscience
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.