Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewRuBi-GABA
Description: Caged GABA; excitable at visible wavelengths
Chemical Name: (bis(2,2'-Bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex
Biological Activity for RuBi-GABA
RuBi-GABA is a ruthenium-bipyridine-triphenylphosphine caged GABA (Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.
Licensing Information
Sold under licence from Columbia University
Technical Data for RuBi-GABA
| M. Wt | 922.8 |
| Formula | C42H39F6N5O2P2Ru |
| Storage | Store at -20°C |
| CAS Number | 1028141-88-9 |
| PubChem ID | 117071637 |
| InChI Key | YMUDUHPMAODLNP-UHFFFAOYSA-N |
| Smiles | [Ru++].NCCCC([O-])=O.F[P-](F)(F)(F)(F)F.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1.C1=CC=C(C=C1)P(C1=CC=CC=C1)C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility for RuBi-GABA
Please refer to these solubility guidelines for RuBi-GABA (Cat. No. 3400).
Product Datasheets for RuBi-GABA
References for RuBi-GABA
References are publications that support the biological activity of the product.
Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882 PMID: 12537482
Rial Verde et al (2008) Photorelease of GABA with visible light using an inorganic caging group. Front.Neural Circuits 2 2 PMID: 18946542
If you know of a relevant reference for RuBi-GABA, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: RuBi-GABA, RuBi-GABA supplier, Caged, GABA, GABAA, GABAC, Receptors, GABAB, Compounds, Miscellaneous, 3400, Tocris Bioscience
1 Citation for RuBi-GABA
Citations are publications that use Tocris products. Selected citations for RuBi-GABA include:
Amatrudo et al (2015) Caged compounds for multichromic optical interrogation of neural systems. Int J Oncol 41 42491 PMID: 25471355
Do you know of a great paper that uses RuBi-GABA from Tocris? Please let us know.
Reviews for RuBi-GABA
There are currently no reviews for this product. Be the first to review RuBi-GABA and earn rewards!
Have you used RuBi-GABA?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.