γ-Secretase Inhibitors

Cat. No.	Product Name / Activity
6363	Avagacestat
	Highly potent γ-secretase inhibitor; orally bioavailable
2870	BMS 299897
	Potent γ-secretase inhibitor
6476	Compound E
	γ-secretase inhibitor; induces neuronal differentiation
2634	DAPT
	γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling
4489	DBZ
	γ-secretase inhibitor; inhibits Notch pathway
2627	L-685,458
	Potent and selective γ-secretase inhibitor
6559	LY 450139
	γ-secretase pseudo-inhibitor
4000	MRK 560
	γ-secretase inhibitor; attenuates amyloid plaque deposition
5751	PF 3084014 hydrobromide
	Potent γ-secretase inhibitor

8151 | VU 0542270
Selective inhibitor of K_ir6.1 K_ATP channels

8813 | RNA Imaging Probe 1c
Fluorogenic RNA imaging probe

7959 | LSN 3318839
Glucagon-like peptide-1 receptor
(GLP1-R) positive allosteric modulator

8170 | CHIR 99021 in solution
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO

8039 | BI 3231
Potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor

Literature in this Area

Stem Cell Research Product Guide

Our guide highlights the use of small molecules in stem cell research and cell therapy and lists relevant products.

Alzheimer's Life Science Poster

Our Alzheimer's disease poster summarizes the genetic, molecular and cellular changes observed in the progression of this neurodegenerative disease.