Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review26RFa
Description: Ligand of GPR103; orexigenic neuropeptide
Alternative Names: P518,QRFP
Biological Activity for 26RFa
Hypothalamic RFamide-related neuropeptide. Acts as a natural ligand of the orphan receptor GPR103. Exhibits orexigenic acitivity in mice upon central administration.
Technical Data for 26RFa
| M. Wt | 2818.18 |
| Formula | C127H197N37O36 |
| Sequence |
VGTALGSLAEELNGYNRKKGGFSFRF (Modifications: Phe-26 = C-terminal amide) |
| Storage | Store at -20°C |
| CAS Number | 881640-56-8 |
| PubChem ID | 90488938 |
| InChI Key | QPWYMHBRJDWMIS-AULSSRMGSA-N |
| Smiles | [H]N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 26RFa
References for 26RFa
References are publications that support the biological activity of the product.
Kampe et al (2006) Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat. Brain Res. 1119 133 PMID: 16996040
Le Marec et al (2011) Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa J.Med.Chem. 54 4806 PMID: 21623631
Chartrel et al (2003) Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc.Natl.Acad.Sci.USA 100 15247 PMID: 14657341
View Related Products by Target
View Related Products by Product Action
Keywords: 26RFa, 26RFa supplier, rfrp, GPR103, ligands, neuropeptides, orexigenic, appetite, stimulating, stimulators, qrfpr, P518, QRFP, Orphan, 7-TM, Receptors, Other, Peptide, 4402, Tocris Bioscience
1 Citation for 26RFa
Citations are publications that use Tocris products. Selected citations for 26RFa include:
Nøhr et al (2017) The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW. Neurochem Int 102 105 PMID: 27916541
Reviews for 26RFa
There are currently no reviews for this product. Be the first to review 26RFa and earn rewards!
Have you used 26RFa?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image