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Submit Review5-OMe-UDP trisodium salt
Description: Potent P2Y6 agonist
Chemical Name: 5-Methoxyuridine 5'-diphosphate trisodium salt
Purity: ≥98% (HPLC)
Biological Activity for 5-OMe-UDP trisodium salt
5-OMe-UDP trisodium salt is a potent P2Y6 agonist (EC50 = 0.08 μM). Displays greater potency at P2Y6 than UDP (Cat.No. 3111) (EC50 = 0.14 μM).
Technical Data for 5-OMe-UDP trisodium salt
| M. Wt | 500.13 |
| Formula | C10H13N2Na3O13P2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| PubChem ID | 90488936 |
| InChI Key | IGMOCSFADHRLMQ-QAUZTDKFSA-K |
| Smiles | [Na+].[Na+].[Na+].COC1CN(C)C(O)N([C@@H]2O[C@H](COP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]2O)C1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 5-OMe-UDP trisodium salt
References for 5-OMe-UDP trisodium salt
References are publications that support the biological activity of the product.
Ginsburg-Shmuel et al (2010) 5-OMe-UDP is a potent and selective P2Y6-receptor agonist. J.Med.Chem. 53 1673 PMID: 20095577
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Keywords: 5-OMe-UDP trisodium salt, 5-OMe-UDP trisodium salt supplier, purinergic, receptors, purinoceptor, p2y6, agonists, purine, receptor, agonist, 1207530-98-0, Purinergic, P2Y, Receptors, 4376, Tocris Bioscience
1 Citation for 5-OMe-UDP trisodium salt
Citations are publications that use Tocris products. Selected citations for 5-OMe-UDP trisodium salt include:
Hansen et al (2013) The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction. Psychopharmacology (Berl) 8 e81491 PMID: 24278446
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.