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Submit ReviewBombinakinin-GAP is a bioactive bradykinin-related peptide. Induces a 60% reduction in food intake following i.c.v. administration in rats.
M. Wt | 3228.75 |
Formula | C145H219N39O39S3 |
Sequence |
DMYEIKQYKTAHGRPPICAPGEQCPIWV (Modifications: Val-28 = C-terminal amide, Disulfide bridge between 18 - 24) |
Storage | Desiccate at -20°C |
CAS Number | 573671-91-7 |
PubChem ID | 90473869 |
InChI Key | WGYUZJQRZYPVMG-BFMDKFMESA-N |
Smiles | [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](C)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C(C)C)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Lai et al (2003) Bombinakinin M gene associated peptide, a novel bioactive peptide from skin secretions of the toad Bombina maxima. Peptides 24 199 PMID: 12668203
Keywords: Bombinakinin-GAP, Bombinakinin-GAP supplier, Bioactive, bradykinin-related, peptide, B1, B2, Receptors, Bradykinin, BombinakininM, Gene, Associated, Peptide, Bombinakinin, M, 2370, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Bombinakinin-GAP include:
Zhang et al (2013) The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval. J Neurosci 33 5006 PMID: 23486971
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