Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewCardionogen 1
Discontinued Product
4475 has been discontinued.
Description: Inhibitor of Wnt/β-catenin signaling
Chemical Name: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
Purity: ≥99% (HPLC)
Biological Activity for Cardionogen 1
Cardionogen 1 is a wnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.
Technical Data for Cardionogen 1
| M. Wt | 274.34 |
| Formula | C13H14N4OS |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 577696-37-8 |
| PubChem ID | 663145 |
| InChI Key | SWTUPSNBTSPBIH-UHFFFAOYSA-N |
| Smiles | C12=NN=C(C3=CC=CO3)N1N=C(C4CCCCC4)S2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Cardionogen 1
References for Cardionogen 1
References are publications that support the biological activity of the product.
Ni et al (2011) Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chem.Biol. 18 1658 PMID: 22195568
View Related Products by Target
Keywords: Cardionogen 1, Cardionogen 1 supplier, Cardionogen1, Wnt/B-catenin, beta-catenin, β-catenin, embryonic, stem, cells, inhibitors, inhibits, cardiac, hyperplasia, differentiation, Beta-catenin, ESCs, and, iPSC, Cardiomyocyte, Stem, Cells, 4475, Tocris Bioscience
Citations for Cardionogen 1
Citations are publications that use Tocris products.
Currently there are no citations for Cardionogen 1.
Reviews for Cardionogen 1
There are currently no reviews for this product. Be the first to review Cardionogen 1 and earn rewards!
Have you used Cardionogen 1?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Pathways for Cardionogen 1
