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Submit ReviewCGP 13501
Description: Positive allosteric modulator of GABAB receptors
Chemical Name: 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal
Purity: ≥98% (HPLC)
Biological Activity for CGP 13501
CGP 13501 is a positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type.
Technical Data for CGP 13501
| M. Wt | 290.44 |
| Formula | C19H30O2 |
| Storage | Desiccate at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 56189-68-5 |
| PubChem ID | 3519541 |
| InChI Key | XGWATTXMMMANFJ-UHFFFAOYSA-N |
| Smiles | CC(C)(C)C1=CC(CC(C)(C)C=O)=CC(=C1O)C(C)(C)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for CGP 13501
References for CGP 13501
References are publications that support the biological activity of the product.
Urwyler et al (2001) Positive allosteric modulation of native and recombinant γ-aminobutyric acidB receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol.Pharmacol. 60 963 PMID: 11641424
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Keywords: CGP 13501, CGP 13501 supplier, Positive, modulators, GABAB, receptors, PAM, CGP13501, Receptors, 1514, Tocris Bioscience
Citations for CGP 13501
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.