Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewCilostazol
Description: PDE3A inhibitor. Also adenosine uptake inhibitor
Chemical Name: 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
Purity: ≥99% (HPLC)
Biological Activity for Cilostazol
Cilostazol is a potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
Compound Libraries for Cilostazol
Cilostazol is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.
Technical Data for Cilostazol
| M. Wt | 369.47 |
| Formula | C20H27N5O2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 73963-72-1 |
| PubChem ID | 2754 |
| InChI Key | RRGUKTPIGVIEKM-UHFFFAOYSA-N |
| Smiles | O=C1CCC2=CC(OCCCCC3=NN=NN3C3CCCCC3)=CC=C2N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Cilostazol
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 3.69 | 10 | |
| DMSO | 18.47 | 50 |
Preparing Stock Solutions for Cilostazol
The following data is based on the product molecular weight 369.47. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 5.41 mL | 27.07 mL | 54.13 mL |
| 2.5 mM | 1.08 mL | 5.41 mL | 10.83 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
| 25 mM | 0.11 mL | 0.54 mL | 1.08 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets for Cilostazol
References for Cilostazol
References are publications that support the biological activity of the product.
Schror (2002) The pharmacology of cilos. Diabetes Obes.Metab. 4 S14 PMID: 12180353
Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system. Arzneimittelforschung 35 1157 PMID: 4074429
Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs. Arzneimittelforschung 35 1163 PMID: 3000392
If you know of a relevant reference for Cilostazol, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Cilostazol, Cilostazol supplier, PDE3A, inhibitors, inhibits, adenosines, reuptake, Phosphodiesterases, ENT1, Purine, Transporters, Pyrimidine, Equilibrative, Nucleoside, Monoamine, Neurotransmitter, 1692, Tocris Bioscience
Citations for Cilostazol
Citations are publications that use Tocris products.
Currently there are no citations for Cilostazol. Do you know of a great paper that uses Cilostazol from Tocris? Please let us know.
Reviews for Cilostazol
There are currently no reviews for this product. Be the first to review Cilostazol and earn rewards!
Have you used Cilostazol?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image