Clindamycin hydrochloride

Discontinued Product

4822 has been discontinued.

View all Antibiotics products.
Description: Antibiotic; inhibits protein synthesis
Chemical Name: Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews (1)

Biological Activity for Clindamycin hydrochloride

Clindamycin hydrochloride is a lincosamide antibiotic. Inhibits protein synthesis by binding to the 50S ribosomal subunit and preventing early peptide chain elongation in bacteria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data for Clindamycin hydrochloride

M. Wt 461.44
Formula C18H33ClN2O5S.HCl
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 21462-39-5
PubChem ID 16051951
InChI Key AUODDLQVRAJAJM-XJQDNNTCSA-N
Smiles CN1[C@H]([C@@](N[C@@]([H])([C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](Cl)C)=O)C[C@@H](CCC)C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Clindamycin hydrochloride

References for Clindamycin hydrochloride

References are publications that support the biological activity of the product.

Champney and Tober (2000) Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr.Microbiol. 41 126 PMID: 10856379

Dhawan and Thadepalli (1982) Clindamycin: a review of fifteen years of experience. Rev.Infect.Dis. 4 1133 PMID: 6818656

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Citations for Clindamycin hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for Clindamycin hydrochloride.

Reviews for Clindamycin hydrochloride

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Clindamycin and Vancomycin combination therapy study.
By Richard Whiteoak on 11/13/2018
Assay Type: In Vitro
Species: Other

Clindamycin and Vancomycin combination therapy was studied. Susceptibility and time kill studies were carried out on MRSA.

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