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Submit ReviewCOR 170
Description: Selective CB2 receptor inverse agonist
Chemical Name: N-(Adamant-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide
Purity: ≥99% (HPLC)
Biological Activity for COR 170
COR 170 is a selective inverse agonist of CB2 receptors (Ki values are 3.8 and >10,000 nM for CB2 and CB1, respectively).
Technical Data for COR 170
| M. Wt | 468.63 |
| Formula | C31H36N2O2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 1048039-15-1 |
| PubChem ID | 25033736 |
| InChI Key | MSJISJDTJJYBFT-UHFFFAOYSA-N |
| Smiles | O=C(C4=CN(CCCCC)C5=C(C=C(C6=CC=CC=C6)C=C5)C4=O)NC12CC(C3)CC(CC3C2)C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for COR 170
References for COR 170
References are publications that support the biological activity of the product.
Pasquini et al (2008) Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. J.Med.Chem. 51 5075 PMID: 18680276
Contartese et al (2012) A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury. Pharmacol.Res. 66 555 PMID: 23036353
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Keywords: COR 170, COR 170 supplier, COR170, CB2, receptors, C2BR, inverse, agonists, selective, cannabinoids, Receptors, 4756, Tocris Bioscience
Citations for COR 170
Citations are publications that use Tocris products.
Currently there are no citations for COR 170.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.