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Submit Review(±)-MDMA hydrochloride
Description: Inhibitor of 5-HT and dopamine uptake; hallucinogenic
Alternative Names: Methylenedioxymethamphetamine hydrochloride
Chemical Name: ±-N,α,-Dimethyl-3,4-methylenedioxyphenethylamine hydrochloride
Purity: ≥98% (HPLC)
Biological Activity for (±)-MDMA hydrochloride
(±)-MDMA hydrochloride is a hallucinogenic compound that inhibits 5-HT and dopamine uptake.
Technical Data for (±)-MDMA hydrochloride
| M. Wt | 229.7 |
| Formula | C11H15NO2.HCl |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 64057-70-1 |
| PubChem ID | 71285 |
| InChI Key | LUWHVONVCYWRMZ-UHFFFAOYSA-N |
| Smiles | CC(NC)CC1=CC(OCO2)=C2C=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (±)-MDMA hydrochloride
References for (±)-MDMA hydrochloride
References are publications that support the biological activity of the product.
Iravani et al (2000) Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or DA release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulata, and the dorsal raphe nucleus slices. Synapse 36 275 PMID: 10819905
Fleckenstein et al (2007) New insights into the mechanism of action of amphetamines. Annu.Rev.Pharmacol.Toxicol. 47 681 PMID: 17209801
Boyle et al (2007) MDMA ("ecstasy") suppresses the innate IFN-γ response in vivo: a critical role for the anti-inflammatory cytokine IL-10. Eur.J.Pharmacol. 572 228 PMID: 17689526
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Keywords: (±)-MDMA hydrochloride, (±)-MDMA hydrochloride supplier, inhibitors, inhibits, 5-HT, dopamine, reuptake, hallucinogenic, Serotonin, Transporters, SERT, 5-Hydroxytryptamine, Monoamine, Neurotransmitter, DAT, Methylenedioxymethamphetamine, hydrochloride, 92279-84-0, (±)-Methylenedioxymethamphetamine, Dopamine, 3027, Tocris Bioscience
Citations for (±)-MDMA hydrochloride
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Currently there are no citations for (±)-MDMA hydrochloride.
Reviews for (±)-MDMA hydrochloride
Average Rating: 5 (Based on 1 Review.)
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Reinstatement of MDMA seeking by exposure to discrete drug-conditioned cues.
By
Kevin Ball on 01/25/2019
Assay Type: In Vivo
Species: Rat
Rats self-administered MDMA (0.30 mg/kg/infusion, i.v.). We then showed that, following extinction of MDMA seeking, discrete MDMA-associated cues reinstated MDMA-seeking behavior. Also, the magnitude of reinstatement was positively correlated with the level of responding during MDMA self-administration.
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.