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Description: Potent tachykinin receptor ligand
Biological Activity for Eledoisin
Eledoisin is a potent natural tachykinin receptor ligand (pD2 values are 9.21, 8.22 and 7.11 for guinea pig NK1, rabbit NK2 and rat NK3 receptors respectively).
Technical Data for Eledoisin
| M. Wt | 1188.4 |
| Formula | C54H85N13O15S |
| Sequence |
XPSKDAFIGLM (Modifications: X = Glp, Met-11 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 69-25-0 |
| PubChem ID | 10328936 |
| InChI Key | AYLPVIWBPZMVSH-FCKMLYJASA-N |
| Smiles | [H]N1[C@@H](CCC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Eledoisin
Safety Datasheet is currently unavailable on-line.
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References for Eledoisin
References are publications that support the biological activity of the product.
Regoli et al (1989) Receptors for substance P and related neurokinins. Pharmacology 38 1 PMID: 2542998
Severini et al (2002) The tachykinin peptide family. Pharmacol.Rev. 54 285 PMID: 12037144
Sturmer et al (1964) Synthetic peptides related to eledoisin. Experientia 20 303 PMID: 5855848
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Keywords: Eledoisin, Eledoisin supplier, Potent, tachykinin, receptor, ligands, Tachykinin, Non-Selective, Neurokinin, Receptors, Other, 1914, Tocris Bioscience
Citations for Eledoisin
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.