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Submit ReviewFuranone C-30 is a synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing in vivo and promotes bacterial clearance in a mouse pulmonary infection model.
M. Wt | 253.88 |
Formula | C5H2Br2O2 |
Storage | Store at -20°C |
Purity | ≥98% |
CAS Number | 247167-54-0 |
PubChem ID | 67228456 |
InChI Key | DPGLBHQUHFJRJS-UHFFFAOYSA-N |
Smiles | Br/C=C1OC(C=C\1Br)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Hentzer et al (2003) Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22 3803 PMID: 12881415
Keywords: Furanone C-30, Furanone C-30 supplier, quorum, sensing, sensors, Gram-negative, signaling, signalling, inhibits, inhibitors, antibacterial, Antibiotics, 6546, Tocris Bioscience
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