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Submit ReviewGalanin (1-15) (porcine, rat)
Description: Galanin receptor agonist peptide
Purity: ≥95% (HPLC)
Biological Activity for Galanin (1-15) (porcine, rat)
N-terminal galanin fragment. In contrast to the full length (1-29) peptide, mediates central cardiovascular effects, perhaps by binding to a novel receptor type.
Technical Data for Galanin (1-15) (porcine, rat)
| M. Wt | 1556.74 |
| Formula | C72H105N19O20 |
| Sequence | GWTLNSAGYLLGPHA |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 112747-70-3 |
| PubChem ID | 16131409 |
| InChI Key | LOXLDVDBPRBBLT-GDRYISODSA-N |
| Smiles | [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Galanin (1-15) (porcine, rat)
References for Galanin (1-15) (porcine, rat)
References are publications that support the biological activity of the product.
Amiranoff et al (1989) Structural requirements for galanin action in the pancreatic β cell line rin m 5F. Eur.J.Pharmacol. 163 205 PMID: 2472967
Narvaez et al (2000) The galanin receptor antagonist M40 blocks the central cardiovascular actions of the galanin N-terminal fragment (1-15). Eur.J.Pharmacol. 399 197 PMID: 10884520
Xu et al (1999) Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neurons. Proc.Natl.Acad.Sci.USA 96 14583 PMID: 10588748
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Keywords: Galanin (1-15) (porcine, rat), Galanin (1-15) (porcine, rat) supplier, Galanin, receptor, agonists, peptide, GAL, GalR, Receptors, 1450, Tocris Bioscience
2 Citations for Galanin (1-15) (porcine, rat)
Citations are publications that use Tocris products. Selected citations for Galanin (1-15) (porcine, rat) include:
Stratford et al (2017) Immunocytochemical organization and sour taste activation in the rostral nucleus of the solitary tract of mice. J Comp Neurol 525 271 PMID: 27292295
Millòn et al (2014) A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats. Int.J.Neuropsychopharmacol. 18 PMID: 25522404
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