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Submit ReviewGalanin (2-29) (rat)
Description: Selective GAL2 peptide agonist
Biological Activity for Galanin (2-29) (rat)
Peptide agonist for galanin receptors, showing selectivity for GAL2 (Ki values are 85, 1.9 and 12.6 nM at rat GAL1, GAL2 and GAL3 receptors respectively).
Technical Data for Galanin (2-29) (rat)
| M. Wt | 3107.42 |
| Formula | C139H207N42O40 |
| Sequence |
WTLNSAGYLLGPHAIDNHRSFSDKHGLT (Modifications: Thr-28 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 141696-11-9 |
| PubChem ID | 90469976 |
| InChI Key | ACSWKWWDLCUVJF-QTRPWDSUSA-N |
| Smiles | [H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Galanin (2-29) (rat)
References for Galanin (2-29) (rat)
References are publications that support the biological activity of the product.
Amiranoff et al (1989) Structural requirements for galanin action in the pancreatic β cell line rin m 5F. Eur.J.Pharmacol. 163 205 PMID: 2472967
Wang et al (1997) Cloning and expressional characterization of a novel galanin receptor. J.Biol.Chem. 272 31949 PMID: 9405385
Wang et al (1997) Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol.Pharmacol. 52 337 PMID: 9281594
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Keywords: Galanin (2-29) (rat), Galanin (2-29) (rat) supplier, Selective, GAL2, GalR2, peptide, agonists, Receptors, Galanin, 1451, Tocris Bioscience
Citations for Galanin (2-29) (rat)
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.