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Submit ReviewGentamicin sulfate is an aminoglycoside antibiotic. Irreversibly binds bacterial ribosomes and disrupts protein synthesis. Active against gram-positive and -negative bacteria. Stable over wide range of temperatures.
Storage | Store at +4°C |
CAS Number | 1405-41-0 |
PubChem ID | 44134731 |
InChI Key | RDEIXVOBVLKYNT-UHFFFAOYSA-N |
Smiles | CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)N.CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CCC(O3)CN)N)N)N)O.OS(=O)(=O)O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility | Soluble to 100 mg/ml in water |
References are publications that support the biological activity of the product.
Casemore (1967) Gentamicin as a bactericidal agent in virological tissue cultures. J.Clin.Pathol. 20 298 PMID: 4972293
Schroeder et al (2000) Modulation of RNA function by aminoglycoside antibiotics. EMBO.J. 4 1 PMID: 10619838
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Keywords: Gentamicin sulfate, Gentamicin sulfate supplier, Gentamicin, Sulfate, antibiotics, aminoglycoside, Antibiotics, 6442, Tocris Bioscience
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Combination of Gentamycin with silver nanoparticles was studied to identify how antibacterial properties differ against E.coli. Different strains of Gentamycin resistant E.coli was also used.
AgNP suspension of 100 ppm was prepared by dissolving 0.1 mg of AgNPs in 1 mL autoclaved deionized water.