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Submit ReviewHeparin sodium salt
Description: Anticoagulant
Biological Activity for Heparin sodium salt
Heparin sodium salt is a minimum activity: > 150 I.U./mg. Glycosaminoglycan that behaves as an anticoagulant. Binds with high affinity to antithrombin III (AT-III). Used in protocols to generate kidney or brain organoids from human pluripotent stem cells.
For more information about how Heparin sodium salt may be used, see our protocol: Generation of Kidney Organoids from hPSCs
Technical Data for Heparin sodium salt
| Storage | Desiccate at RT |
| CAS Number | 9041-08-1 |
| PubChem ID | 25244225 |
| InChI Key | OHJKXVLJWUPWQG-IUYNYSEKSA-J |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Heparin sodium salt
| Solubility | Soluble to 50 mg/ml in water |
Product Datasheets for Heparin sodium salt
References for Heparin sodium salt
References are publications that support the biological activity of the product.
Lever and Page (2002) Novel drug development opportunities for he. Nat.Rev.Drug Discov. 1 140 PMID: 12120095
Takasato et al (2016) Generation of kidney organoids from human pluripotent stem cells. Nat.Protoc. 11 1681 PMID: 1681
Schafer (2023) An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell 186 1222 PMID: 37172564
If you know of a relevant reference for Heparin sodium salt, please let us know.
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Keywords: Heparin sodium salt, Heparin sodium salt supplier, Anticoagulant, heparin, Adhesion, Molecules, antithrombin, III, organoids, Cell, Organoids, 2812, Tocris Bioscience
7 Citations for Heparin sodium salt
Citations are publications that use Tocris products. Selected citations for Heparin sodium salt include:
Bousquenaud et al (2012) Monocyte chemotactic protein 3 is a homing factor for circulating angiogenic cells. Hum Mol Genet 94 519 PMID: 22492674
Bakri et al (2016) Embryo apoptosis identification: Oocyte grade or cleavage stage? Saudi J Biol Sci 23 S50 PMID: 26858565
Srinivasan et al (2018) Androgen receptor expression reduces stemness characteristics of prostate cancer cells (PC3) by repression of CD44 and SOX2. J Cell Biochem PMID: 30206982
Schafer et al (2023) An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell 186 2111 PMID: 37172564
Battefeld et al (2019) High-Frequency Microdomain Ca2+ Transients and Waves during Early Myelin Internode Remodeling. Cell Rep 26 182 PMID: 30605675
You et al (2015) Impact of Nanotopography, he. Hydrogel Microstructures, and Encapsulated Fibroblasts on Phenotype of Primary Hepatocytes. ACS Appl Mater Interfaces 7 12299 PMID: 25247391
Zhou et al (2019) Angiopoietin-2 induces the neuronal differentiation of mouse embryonic NSCs via phosphatidylinositol 3 kinase-Akt pathway-mediated phosphorylation of mTOR. Am J Transl Res 11 1895 PMID: 30972213
Do you know of a great paper that uses Heparin sodium salt from Tocris? Please let us know.
Reviews for Heparin sodium salt
Average Rating: 5 (Based on 1 Review.)
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We used Heparin sodium salt to stimulate proliferation of primary epithelial cells.
By
Meghan Bradshaw on 02/25/2019
Species: Human
We used Heparin sodium salt to stimulate proliferation of primary epithelial cells.Heparin solutions were sterilized by filtering through a sterilemembrane filter with a porosity of 0.22micron or less.
Do not autoclave heparin solutions
