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Description: α4β1 (VLA-4) ligand
Purity: ≥95% (HPLC)
Biological Activity for LDV
LDV is a α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC (Cat. No. 4577).
Technical Data for LDV
| M. Wt | 979.13 |
| Formula | C48H70N10O12 |
| Sequence | LDVPAAK (Modifications: Leu-1 = N-2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl-Leu) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 1155866-55-9 |
| InChI Key | FQYZPSNPTJYQKB-CGTMUHGOSA-N |
| Smiles | CC(C)C[C@@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)C)=O)C)=O)=O)C(C)C)=O)CC(O)=O)=O)NC(CC(C=C2)=CC=C2NC(NC3=C(C)C=CC=C3)=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for LDV
| Solubility | Soluble to 1 mg/ml in 0.01M PBS (pH 7.4) |
Product Datasheets for LDV
References for LDV
References are publications that support the biological activity of the product.
Chigaev et al (2009) Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. J.Biol.Chem. 284 14337 PMID: 19251697
If you know of a relevant reference for LDV, please let us know.
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Keywords: LDV, LDV supplier, VLA4, very, late, antigen, 4, ligand, integrin, a4b1, alpha4beta1, Integrins, 7020, Tocris Bioscience
Citations for LDV
Citations are publications that use Tocris products.
Currently there are no citations for LDV. Do you know of a great paper that uses LDV from Tocris? Please let us know.
Reviews for LDV
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Literature in this Area
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Angiogenesis in Cancer Poster
This poster summarizes the pathogenesis of angiogenesis in cancer, as well as some of the main angiogenesis therapeutic targets.
