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Submit ReviewBiological Activity for LRGILS-NH2
LRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.
Active Analog also available.
Technical Data for LRGILS-NH2
| M. Wt | 656.83 |
| Formula | C29H56N10O7 |
| Sequence |
LRGILS (Modifications: Ser-6 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 245329-01-5 |
| PubChem ID | 90488840 |
| InChI Key | HCUFWKYFOMBFPA-JYAZKYGWSA-N |
| Smiles | [H]N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for LRGILS-NH2
| Solubility | Soluble to 2 mg/ml in water |
Product Datasheets for LRGILS-NH2
References for LRGILS-NH2
References are publications that support the biological activity of the product.
Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717
Nishikawa et al (2005) Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in Rats: Involvement of PAR-2 and non-PAR-2 mechanisms. J.Pharmacol.Exp.Ther. 312 324 PMID: 15331653
Devlin et al (2007) Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice. Parasitol.Res. 101 105 PMID: 17458579
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Keywords: LRGILS-NH2, LRGILS-NH2 supplier, Control, peptide, SLIGRL-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3394, Tocris Bioscience
Citations for LRGILS-NH2
Citations are publications that use Tocris products.
Currently there are no citations for LRGILS-NH2. Do you know of a great paper that uses LRGILS-NH2 from Tocris? Please let us know.
Reviews for LRGILS-NH2
Average Rating: 4 (Based on 1 Review.)
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Good and easy product to use for regular in-vitro stimulations.
By
Anonymous on 11/20/2019
Assay Type: In Vitro
Species: Human
Cell Line/Tissue: Smooth Muscle Cells
Was used in an in-vitro stimulation assay as a control peptide