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Submit ReviewMRS 2690
Description: Potent P2Y14 agonist
Chemical Name: Diphosphoric acid 1-α-D-glucopyranosyl ester 2-[(4'-methylthio)uridin-5''-yl] ester disodium salt
Purity: ≥98% (HPLC)
Biological Activity for MRS 2690
MRS 2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
This product is typically reconstituted in water.
Technical Data for MRS 2690
| M. Wt | 626.33 |
| Formula | C15H22N2Na2O16P2S |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| PubChem ID | 73755042 |
| InChI Key | TYVFMVSNSGMZPA-QBNUFUENSA-L |
| Smiles | [Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=S)[C@H](O)[C@@H](O)[C@@H]1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MRS 2690
References for MRS 2690
References are publications that support the biological activity of the product.
Ko et al (2007) Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J.Med.Chem. 50 2030 PMID: 17407275
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Keywords: MRS 2690, MRS 2690 supplier, Potent, P2Y14, agonists, Receptors, Purinergic, purinoceptors, MRS2690, 15039-58-4, P2Y, 2915, Tocris Bioscience
1 Citation for MRS 2690
Citations are publications that use Tocris products. Selected citations for MRS 2690 include:
Gao et al (2013) The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells. Neuropsychopharmacology 9 31 PMID: 22825617
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Reviews for MRS 2690
Average Rating: 5 (Based on 1 Review.)
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Filter by:
P2Y14 agonist.
By
Anonymous on 09/20/2018
Assay Type: Ex Vivo
Species: Mouse
P2Y14 activation.
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.