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Submit ReviewMRS 4062 triethylammonium salt
Description: Selective P2Y4 receptor agonist
Chemical Name: N4-Phenylpropoxycytidine-5'-O-triphosphate tetra(triethylammonium) salt
Purity: ≥98% (HPLC)
Biological Activity for MRS 4062 triethylammonium salt
MRS 4062 triethylammonium salt is a selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively).
Technical Data for MRS 4062 triethylammonium salt
| M. Wt | 1022.09 |
| Formula | C18H26N3O15P3.4(C2H5)3N |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1309871-50-8 |
| PubChem ID | 90488925 |
| InChI Key | ZCDZFMKRHPANNI-IHQKQWLFSA-N |
| Smiles | O[C@@H]1[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N3C(N/C(C=C3)=N\OCCCC2=CC=CC=C2)=O)[C@@H]1O.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for MRS 4062 triethylammonium salt
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Product Datasheets for MRS 4062 triethylammonium salt
References for MRS 4062 triethylammonium salt
References are publications that support the biological activity of the product.
Maruoka et al (2011) Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphate δ-ester modifications as selective agonists of the P2Y4 receptor. J.Med.Chem. 54 4018 PMID: 21528910
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1 Citation for MRS 4062 triethylammonium salt
Citations are publications that use Tocris products. Selected citations for MRS 4062 triethylammonium salt include:
Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050 PMID: 24048730
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.