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Submit ReviewMuramyl Dipeptide
Description: Activates NOD2 receptors
Chemical Name: N-Acetylmuramoyl-L-alanyl-D-α-glutamine
Purity: ≥98% (HPLC)
Biological Activity for Muramyl Dipeptide
Muramyl Dipeptide is a bacterial peptidoglycan fragment that activates NOD2 receptors. Induces polarization of proinflammatory Ly6Chigh into Ly6Clow patrolling monocytes.
Technical Data for Muramyl Dipeptide
| M. Wt | 492.48 |
| Formula | C19H32N4O11 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 53678-77-6 |
| PubChem ID | 451714 |
| InChI Key | BSOQXXWZTUDTEL-ZUYCGGNHSA-N |
| Smiles | C[C@@H](O[C@@H]1[C@@H](NC(C)=O)C(O)O[C@H](CO)[C@H]1O)C(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Muramyl Dipeptide
References for Muramyl Dipeptide
References are publications that support the biological activity of the product.
Lessard et al (2017) Triggering of NOD2 receptor converts inflammatory Ly6Chigh into Ly6Clow monocytes with patrolling properties. Cell Rep. 20 1830 PMID: 28834747
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Keywords: Muramyl Dipeptide, Muramyl Dipeptide supplier, NOD2, nod-like, receptors, activates, activators, bacterial, peptidoglycan, innate, immunity, pattern, recognition, Inflammasomes, 6366, Tocris Bioscience
Citations for Muramyl Dipeptide
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