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MY-5445

Cat. No. 0432 1 Review Submit a Review Datasheet / COA / SDS

Discontinued Product

0432 has been discontinued.

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Description: PDE5 inhibitor
Chemical Name: 1-(3-Chlorophenylamino)-4-phenylphthalazine
Datasheet
Citations
Reviews (1)
Biological Activity Technical Data Datasheets References

Biological Activity for MY-5445

Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).

Technical Data for MY-5445

M. Wt 331.8
Formula C20H14ClN3
Storage Store at RT
CAS Number 78351-75-4
PubChem ID 1348
InChI Key CEHQLKSLMFIHBF-UHFFFAOYSA-N
Smiles ClC1=CC(NC2=C3C=CC=CC3=C(N=N2)C2=CC=CC=C2)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for MY-5445

References are publications that support the biological activity of the product.

Hagiwara et al (1984) Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. J.Pharmacol.Exp.Ther. 228 467 PMID: 6141286

Hidaka and Endo et al (1984) Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications. Adv.Cyclic Nucleotide Protein Phosphorylation Res. 16 245 PMID: 6144253

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Keywords: MY-5445, MY-5445 supplier, PDE5, inhibitors, inhibits, PDE, Phosphodiesterases, MY, 5445, 0432, Tocris Bioscience

Citations for MY-5445

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Currently there are no citations for MY-5445.

Reviews for MY-5445

Average Rating: 4 (Based on 1 Review.)

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Great product.
By Abhijit Nirwane on 01/08/2018
Assay Type: In Vivo
Species: Other

In vivo reproductive studies