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Submit ReviewN-Methylquipazine dimaleate is a 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.
M. Wt | 459.45 |
Formula | C14H17N3.(C4H4O4)2 |
Storage | Store at RT |
CAS Number | 171205-17-7 |
PubChem ID | 11957670 |
InChI Key | HNSITEGFVDCKMF-SPIKMXEPSA-N |
Smiles | OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CC1)C1=NC2=C(C=CC=C2)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Glennon et al (1989) Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study. Eur.J.Pharmacol. 168 387 PMID: 2583244
Keywords: N-Methylquipazine dimaleate, N-Methylquipazine dimaleate supplier, 5-HT3, agonists, Serotonin, Receptors, 0566, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.