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Submit ReviewNB-caged Tyrosine hydrochloride
Description: ortho-nitrobenzyl caged L- tyrosine
Alternative Names: ONBY
Chemical Name: O-[(2-Nitrophenyl)methyl]-L-tyrosine hydrochloride
Purity: ≥97% (HPLC)
Biological Activity for NB-caged Tyrosine hydrochloride
NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitive ortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated into E.coli proteins via inclusion in growth media.
Technical Data for NB-caged Tyrosine hydrochloride
| M. Wt | 352.77 |
| Formula | C16H16N2O5.HCl |
| Storage | Store at -20°C |
| Purity | ≥97% (HPLC) |
| CAS Number | 207727-86-4 |
| PubChem ID | 53393436 |
| InChI Key | DRUCEARMIBXBOJ-UQKRIMTDSA-N |
| Smiles | N[C@H](C(O)=O)CC1=CC=C(C=C1)OCC2=C([N+]([O-])=O)C=CC=C2.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for NB-caged Tyrosine hydrochloride
References for NB-caged Tyrosine hydrochloride
References are publications that support the biological activity of the product.
Miller et al (1998) Flash decaging of tyrosine sidechains in an ion channel. Neuron. 20 619 PMID: 9581754
Monk et al (2017) Rapid and inexpensive evaluation of nonstandard amino acid incorporation in Escherichia coli. ACS.Synth.Biol. 6 45 PMID: 27648665
Wang et al (2019) Time-resolved protein activation by proximal decaging in living systems. Nature 569 509 PMID: 31068699
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Citations for NB-caged Tyrosine hydrochloride
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