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Submit ReviewNeurokinin A (porcine)
Description: Endogenous tachykinin peptide
Alternative Names: NKA
Biological Activity for Neurokinin A (porcine)
Endogenous tachykinin peptide; more potent bronchoconstrictor than Substance P.
Technical Data for Neurokinin A (porcine)
| M. Wt | 1133.3 |
| Formula | C50H80N14O14S |
| Sequence |
HKTDSFVGLM (Modifications: Met-10 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 86933-74-6 |
| PubChem ID | 5311311 |
| InChI Key | HEAUFJZALFKPBA-JPQUDPSNSA-N |
| Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Neurokinin A (porcine)
References for Neurokinin A (porcine)
References are publications that support the biological activity of the product.
Lippe et al (1997) Neurokinin A-induced vasoconstriction and muscular contraction in the rat isolated stomach: mediation by distinct and unusual neurokinin A2 receptors. J.Pharmacol.Exp.Ther. 281 1294 PMID: 9190865
Nawa et al (1983) Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor. Nature 306 32 PMID: 6195531
Sherwood et al (1997) Bronchoconstrictor and respiratory effects of neurokinin A in dogs. J.Pharmacol.Exp.Ther. 283 788 PMID: 9353399
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Keywords: Neurokinin A (porcine), Neurokinin A (porcine) supplier, Endogenous, tachykinin, peptide, Non-Selective, Neurokinin, Receptors, agonists, NeurokininA, NKA, Other, Tachykinin, 1152, Tocris Bioscience
1 Citation for Neurokinin A (porcine)
Citations are publications that use Tocris products. Selected citations for Neurokinin A (porcine) include:
Gutierrez and Boada (2019) Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+). Cancer Cell Int 18 216 PMID: 30598641
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.