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Submit ReviewNeuropathiazol
Description: Selective inducer of neuronal differentiation in hippocampal neural progenitors
Chemical Name: Ethyl 4-[methyl-(2-phenyl-1,3-thiazol-4-yl)amino]benzoate
Purity: ≥98% (HPLC)
Biological Activity for Neuropathiazol
Neuropathiazol is a selective inducer of neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs). Selectively suppresses astrocyte differentiation when induced by LIF, BMP2 and FBS compared to retinoic acid. Enhances maturation of NPC derived neurons.
Technical Data for Neuropathiazol
| M. Wt | 338.42 |
| Formula | C19H18N2O2S |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 880090-88-0 |
| PubChem ID | 11667240 |
| InChI Key | MGKYEWWFHSESJN-UHFFFAOYSA-N |
| Smiles | O=C(OCC)C1=CC=C(N(C2=CSC(C3=CC=CC=C3)=N2)C)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Neuropathiazol
References for Neuropathiazol
References are publications that support the biological activity of the product.
Warashina et al (2006) A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angew Chem. Int. Ed. Engl. 45 591 PMID: 16323231
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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