Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Reviewo-3M3FBS is an inactive analog of m-3M3FBS. Used as a negative control.
Active Analog also available.
o-3M3FBS is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.
M. Wt | 343.36 |
Formula | C16H16F3NO2S |
Storage | Store at RT |
Purity | ≥99% (HPLC) |
CAS Number | 313981-55-4 |
PubChem ID | 770820 |
InChI Key | SKJJIFRWCCSXGL-UHFFFAOYSA-N |
Smiles | CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=C(C=CC=C1)C(F)(F)F |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
ethanol | 34.34 | 100 | |
DMSO | 34.34 | 100 |
The following data is based on the product molecular weight 343.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.91 mL | 14.56 mL | 29.12 mL |
5 mM | 0.58 mL | 2.91 mL | 5.82 mL |
10 mM | 0.29 mL | 1.46 mL | 2.91 mL |
50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
References are publications that support the biological activity of the product.
Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532
If you know of a relevant reference for o-3M3FBS, please let us know.
Keywords: o-3M3FBS, o-3M3FBS supplier, Phospholipases, C, PLC, Esterases, activators, Phospholipase, 1942, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for o-3M3FBS include:
Wilke et al (2014) Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun 5 5540 PMID: 25420509
Szebenyi et al (2014) Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons. Front Cell Neurosci 8 336 PMID: 25374507
Carim et al (2019) IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol 29 775 PMID: 30799246
Semple-Rowland et al (2014) Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8 e83378 PMID: 24386190
Krjukova et al (2004) Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol 143 3 PMID: 15302681
Horowitz et al (2005) Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. PLoS One 126 243 PMID: 16129772
Do you know of a great paper that uses o-3M3FBS from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review o-3M3FBS and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image