Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review[Orn5]-URP
Description: Urotensin-II (UT) receptor antagonist
Biological Activity for [Orn5]-URP
[Orn5]-URP is an urotensin-II (UT) receptor pure antagonist (pEC50 = 7.24). Displays no agonist activity unlike other U-II/URP analogs. Inhibits the action of U-II in the rat aorta ring assay.
Technical Data for [Orn5]-URP
| M. Wt | 1003.2 |
| Formula | C48H62N10O10S2 |
| Sequence |
ACFWXYCV (Modifications: X = Orn, Disulfide bridge between 2 - 7) |
| Storage | Store at -20°C |
| CAS Number | 782485-03-4 |
| PubChem ID | 90488807 |
| InChI Key | BPLKRLYKWHXTMO-LSKWFVNGSA-N |
| Smiles | [H]N[C@@H](C)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](C(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for [Orn5]-URP
References for [Orn5]-URP
References are publications that support the biological activity of the product.
Chatenet et al (2004) Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides 25 1819 PMID: 15476952
Diallo et al (2008) [Orn5]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes. Peptides 29 813 PMID: 18082287
View Related Products by Target
View Related Products by Product Action
Keywords: [Orn5]-URP, [Orn5]-URP supplier, Urotensin-II, UT, receptor, antagonists, Receptors, 3162, Tocris Bioscience
1 Citation for [Orn5]-URP
Citations are publications that use Tocris products. Selected citations for [Orn5]-URP include:
Lee et al (2014) Urotensin II induces interleukin 8 expression in human umbilical vein endothelial cells. PLoS One 9 e90278 PMID: 24587311
Reviews for [Orn5]-URP
There are currently no reviews for this product. Be the first to review [Orn5]-URP and earn rewards!
Have you used [Orn5]-URP?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image