Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewPEN (human)
Description: GPR83 agonist
Alternative Names: pro-SAAS (221-242)
Biological Activity for PEN (human)
PEN (human) is a endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
Technical Data for PEN (human)
| M. Wt | 2215.49 |
| Formula | C97H159N27O32 |
| Sequence | AADHDVGSELPPEGVLGALLRV |
| Storage | Store at -20°C |
| CAS Number | 597578-70-6 |
| PubChem ID | 16139549 |
| InChI Key | PEIJMGIGWZOADR-UCVVRVGMSA-N |
| Smiles | [H]N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for PEN (human)
References for PEN (human)
References are publications that support the biological activity of the product.
Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal 9 ra43 PMID: 27117253
Mack et al (2019) Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. ACS Chem Neurosci. 10 1884 PMID: 30726666
View Related Products by Target
View Related Products by Product Action
Keywords: PEN (human), PEN (human) supplier, GPR83, agonists, agonism, neuropeptide, JP05, GPR72, glucocorticoid-induced, receptor, pro-SAAS, (221-242), 6307, Tocris Bioscience
Citations for PEN (human)
Citations are publications that use Tocris products.
Currently there are no citations for PEN (human).
Reviews for PEN (human)
There are currently no reviews for this product. Be the first to review PEN (human) and earn rewards!
Have you used PEN (human)?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Gut Hormones Poster
The gastrointestinal tract is the largest endocrine gland in the human body, secreting hormones that affect digestion, appetite and energy expenditure. Neuropeptide modulators and gut hormones that influence appetite are reviewed in this poster.