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Submit ReviewPhenobarbital sodium salt
Description: Enhances GABAergic activity
Chemical Name: 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Biological Activity for Phenobarbital sodium salt
Enhances GABAergic activity. Long-acting barbiturate; slow-acting barbiturate (Cat. No. 4579) also available.
Technical Data for Phenobarbital sodium salt
| M. Wt | 254.22 |
| Formula | C12H11N2NaO3 |
| Storage | Store at RT |
| CAS Number | 57-30-7 |
| PubChem ID | 12598276 |
| InChI Key | WRLGYAWRGXKSKG-UHFFFAOYSA-M |
| Smiles | [Na+].CCC1(C(=O)NC([O-])=NC1=O)C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Phenobarbital sodium salt
Certificate of Analysis is currently unavailable on-line.
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References for Phenobarbital sodium salt
References are publications that support the biological activity of the product.
Nardou et al (2011) Phenobarbital but not D.pam reduces AMPA/kainate receptor mediated currents and exerts opposite actions on initial seizures in the neonatal rat hippocampus. Front.Cell.Neurosci. 5 Epub PMID: 21847371
ffrench-Mullen et al (1993) Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current. J.Neurosci. 13 3211 PMID: 8101867
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Keywords: Phenobarbital sodium salt, Phenobarbital sodium salt supplier, Phenobarbital, barbiturates, anticonvulsants, GABAergic, GABA, Miscellaneous, GABAB, Receptors, 4578, Tocris Bioscience
Citations for Phenobarbital sodium salt
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.