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Submit ReviewRizatriptan benzoate is a 5-HT1B/1D agonist. Antimigraine agent; attenuates effects of CGRP on light aversion in mice. Orally bioavailable.
Rizatriptan benzoate is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.
M. Wt | 391.47 |
Formula | C15H19N5.C7H6O2 |
Storage | Store at RT |
Purity | ≥99% (HPLC) |
CAS Number | 145202-66-0 |
PubChem ID | 77997 |
InChI Key | JPRXYLQNJJVCMZ-UHFFFAOYSA-N |
Smiles | CN(CCC2=CNC1=CC=C(CN3N=CN=C3)C=C12)C.O=C(C4=CC=CC=C4)O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Kaiser et al (2012) Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT1B/D agonist. J.Neurosci. 32 15439 PMID: 23115181
Street et al (1995) Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors. J.Med.Chem. 38 1799 PMID: 7752204
Keywords: Rizatriptan benzoate, Rizatriptan benzoate supplier, selective, 5-HT, serotonin, 5-HT1D, 5-HT1B, receptors, agonists, Rizatriptan, benzoate, serotonergics, MK462, MK, 462, Receptors, 5136, Tocris Bioscience
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