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Description: Potent PDE9 inhibitor
Chemical Name: 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Purity: ≥98% (HPLC)
Biological Activity for (S)-C33
(S)-C33 is a potent PDE9 inhibitor (IC50 = 11 nM).
Technical Data for (S)-C33
| M. Wt | 357.84 |
| Formula | C18H20ClN5O |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 2066488-39-7 |
| PubChem ID | 91885385 |
| InChI Key | CRRDKKMBUNVLKQ-NSHDSACASA-N |
| Smiles | C[C@@H](C1=CC=C(C=C1)Cl)NC2=NC(C3=C(N(C4CCCC4)N=C3)N2)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (S)-C33
References for (S)-C33
References are publications that support the biological activity of the product.
Huang et al (2015) Structural asymmetry of phosphodiesterase-9A and a unique pocket for selective binding of a potent enantiomeric inhibitor. Mol.Pharmacol. 88 836 PMID: 26316540
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Keywords: (S)-C33, (S)-C33 supplier, phosphodiesterase, PDE9, inhibitor, Potent, SC33, Phosphodiesterases, 6035, Tocris Bioscience
Citations for (S)-C33
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