Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewSulprostone
Description: EP3 and EP1 receptor agonist
Chemical Name: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
Biological Activity for Sulprostone
Sulprostone is a selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.
Technical Data for Sulprostone
| M. Wt | 465.56 |
| Formula | C23H31NO7S |
| Storage | Store at -20°C |
| CAS Number | 60325-46-4 |
| PubChem ID | 5312153 |
| InChI Key | UQZVCDCIMBLVNR-TWYODKAFSA-N |
| Smiles | O=C1[C@H](C/C=C\CCCC(NS(=O)(C)=O)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)[C@H](O)C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Sulprostone
References for Sulprostone
References are publications that support the biological activity of the product.
Gil et al (2008) Transient allodynia pain models in mice for assessment of analgesic activity. Br.J.Pharmacol. 153 769 PMID: 17700719
Narumiya et al (1999) Prostanoid receptors: Structures, properties, and functions. Phys.Rev. 79 1193
View Related Products by Target
View Related Products by Product Action
Keywords: Sulprostone, Sulprostone supplier, Sulprostone, prostaglandin, prostanoid, EP1, EP3, receptor, agonist, Prostanoid, Receptors, 3049, Tocris Bioscience
1 Citation for Sulprostone
Citations are publications that use Tocris products. Selected citations for Sulprostone include:
Ye et al (2018) Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses. Endocr Connect 7 749 PMID: 29700097
Reviews for Sulprostone
There are currently no reviews for this product. Be the first to review Sulprostone and earn rewards!
Have you used Sulprostone?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image