Home / Pharmacology / GPCRs / 7-TM Receptors / Orphan 7-TM Receptors / Orphan 7-TM Receptor Agonists / TC-O 9311

TC-O 9311

Cat. No. 4255 1 Citation Submit a Review Datasheet / COA / SDS

Discontinued Product

4255 has been discontinued.

View all Orphan 7-TM Receptors products.
Description: Potent and selective GPR139 agonist
Chemical Name: 3,5-Dimethoxybenzoic acid 2-[(1-naphthalenylamino)carbonyl]hydrazide
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Biological Activity Technical Data Datasheets References

Biological Activity for TC-O 9311

TC-O 9311 is a potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GPR139). Displays no activity against a range of 90 diverse targets.

Compound Libraries for TC-O 9311

TC-O 9311 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for TC-O 9311

M. Wt 365.38
Formula C20H19N3O4
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 444932-31-4
PubChem ID 3376937
InChI Key KPTMSQHTGZMEFU-UHFFFAOYSA-N
Smiles O=C(NNC(NC2=CC=CC3=C2C=CC=C3)=O)C1=CC(OC)=CC(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for TC-O 9311

References are publications that support the biological activity of the product.

Shi et al (2011) Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139. ACS Med.Chem.Lett. 2 303 PMID: 24900311

View Related Products by Target

View Related Products by Product Action

View all Orphan 7-TM Receptor Agonists

Keywords: TC-O 9311, TC-O 9311 supplier, TCO9311, gpr139, receptors, orphan, potent, selective, agonists, Orphan, 7-TM, Receptors, 4255, Tocris Bioscience

1 Citation for TC-O 9311

Citations are publications that use Tocris products. Selected citations for TC-O 9311 include:

Nepomuceno et al (2018) Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro. Front Pharmacol 9 157 PMID: 29599718

Reviews for TC-O 9311

There are currently no reviews for this product. Be the first to review TC-O 9311 and earn rewards!

Have you used TC-O 9311?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review