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Submit ReviewTiclopidine hydrochloride
Description: Selective P2Y12 antagonist
Chemical Name: 5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride
Purity: ≥99% (HPLC)
Biological Activity for Ticlopidine hydrochloride
Selective P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.
Technical Data for Ticlopidine hydrochloride
| M. Wt | 300.25 |
| Formula | C14H14ClNS.HCl |
| Storage | Desiccate at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 53885-35-1 |
| PubChem ID | 65335 |
| InChI Key | MTKNGOHFNXIVOS-UHFFFAOYSA-N |
| Smiles | ClC(C=CC=C3)=C3CN1CCC2=C(C=CS2)C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Ticlopidine hydrochloride
References for Ticlopidine hydrochloride
References are publications that support the biological activity of the product.
Michelson (2008) P2Y12 antagonism: promises and challenges. Arterioscler.Thromb.Vasc.Biol. 28 33
Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174
Sharis et al (1998) The antiplatelet effects of ticlop. and clopid. Ann.Int.Med. 129 394
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Keywords: Ticlopidine hydrochloride, Ticlopidine hydrochloride supplier, selective, P2Y12, purinergic, receptors, purinoceptors, antagonists, Purinergic, P2Y, Receptors, 3931, Tocris Bioscience
Citations for Ticlopidine hydrochloride
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Currently there are no citations for Ticlopidine hydrochloride.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.