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Submit ReviewTobramycin
Description: Aminoglycoside antibiotic
Chemical Name: O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine
Biological Activity for Tobramycin
Tobramycin is an aminoglycoside antibiotic. Exhibits antibacterial activity against strains of Enterobacteriaceae, Pseudomonas and Staphylococcus aureus. Shown to protect lung epithelial cells in vitro against injury from cystic fibrosis bronchial secretions and H2O2.
Technical Data for Tobramycin
| M. Wt | 467.52 |
| Formula | C18H37N5O9 |
| Storage | Store at +4°C |
| CAS Number | 32986-56-4 |
| PubChem ID | 36294 |
| InChI Key | NLVFBUXFDBBNBW-PBSUHMDJSA-N |
| Smiles | O[C@H]1C[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@@H]1CN |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Tobramycin
References for Tobramycin
References are publications that support the biological activity of the product.
Dienstag and Neu (1972) In vitro studies of tobramycin, an aminoglycoside antibiotic. Antimicrob.Agents Chemother. 1 41 PMID: 4670427
Cantin and Woods (1993) Protection by antibiotics against myeloperoxidase-dependent cytotoxicity to lung epithelial cells in vitro. PMID: 8380814
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Keywords: Tobramycin, Tobramycin supplier, aminoglycoside, antibiotics, antibacterial, Antibiotics, 5390, Tocris Bioscience
Citations for Tobramycin
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Currently there are no citations for Tobramycin.
Reviews for Tobramycin
Average Rating: 5 (Based on 1 Review.)
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Mechanism of action of tobramycin studied against gentamicin and neomycin m/a.
By
Anonymous on 11/30/2019
Species: Human
Mechanism of action of tobramycin was studied along with other aminoglycoside antibiotics such as neomycin and gentamicin.Clinical isolate of P. aeruginosa, PAO1 (PAO1-RH) used to do susceptibility tests.
