Tropanyl-3,5-dimethylbenzoate

Discontinued Product

0641 has been discontinued.

View all 5-HT<sub>3</sub> Receptors products.
Description: 5-HT3 antagonist
Purity: ≥99%
Datasheet
Citations (2)
Reviews
Literature (1)

Biological Activity for Tropanyl-3,5-dimethylbenzoate

Tropanyl-3,5-dimethylbenzoate is a 5-HT3 antagonist.

Technical Data for Tropanyl-3,5-dimethylbenzoate

M. Wt 273.37
Formula C17H23NO2
Storage Store at RT
Purity ≥99%
CAS Number 85181-40-4
PubChem ID 2837530
InChI Key HDDNYFLPWFSBLN-UHFFFAOYSA-N
Smiles CN1C2CCC1CC(C2)OC(=O)C1=CC(C)=CC(C)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Tropanyl-3,5-dimethylbenzoate

References for Tropanyl-3,5-dimethylbenzoate

References are publications that support the biological activity of the product.

Fozard and Gitto (1983) Selective blockade of 5-hydroxytryptamine neuronal receptors by benzoic acid esters of tropine. Br.J.Pharmacol. 80 511P

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Keywords: Tropanyl-3,5-dimethylbenzoate, Tropanyl-3,5-dimethylbenzoate supplier, 5-HT3, antagonists, Serotonin, Receptors, 0641, Tocris Bioscience

2 Citations for Tropanyl-3,5-dimethylbenzoate

Citations are publications that use Tocris products. Selected citations for Tropanyl-3,5-dimethylbenzoate include:

Yang et al (2010) Activation of submucosal 5-HT(3) receptors elicits a somatostatin-dependent inhibition of ion secretion in rat colon. Br J Pharmacol 159 1623 PMID: 20233224

Dolma et al (2016) Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell 29 859 PMID: 27300435


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


5-HT Receptors Scientific Review

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.